Hypoxia dose painting by numbers: a planning study
D Thorwarth, SM Eschmann, F Paulsen… - International Journal of …, 2007 - Elsevier
Purpose: To investigate the feasibility of different hypoxia dose painting strategies in head-
and-neck radiotherapy; the potential benefit was limited by the stipulation of isotoxicity with
respect to the conventional intensity-modulated radiotherapy (IMRT) treatment. Methods and
Materials: Thirteen head-and-neck cancer patients were included into the planning study.
For each patient, three different treatment plans were created: a conventional IMRT plan, an
additional uniform dose escalation (uniDE) of 10% to the fluorodeoxyglucose (FDG)-positive …
and-neck radiotherapy; the potential benefit was limited by the stipulation of isotoxicity with
respect to the conventional intensity-modulated radiotherapy (IMRT) treatment. Methods and
Materials: Thirteen head-and-neck cancer patients were included into the planning study.
For each patient, three different treatment plans were created: a conventional IMRT plan, an
additional uniform dose escalation (uniDE) of 10% to the fluorodeoxyglucose (FDG)-positive …