High-resolution myocardial perfusion imaging in mice with high-frequency echocardiographic detection of a depot contrast agent
BA Kaufmann, M Lankford, CZ Behm, BA French… - Journal of the American …, 2007 - Elsevier
High-resolution methods for assessing myocardial perfusion in murine models of
cardiovascular disease are needed. We hypothesized that regional hypoperfusion could be
assessed with ultrahigh-frequency myocardial contrast echocardiography (MCE) and a
novel strategy of depot contrast enhancement. MCE was performed with 30-MHz
transthoracic imaging 10 seconds and 10 minutes after intravenous administration of
microbubbles in control mice, and in mice after left anterior descending coronary artery …
cardiovascular disease are needed. We hypothesized that regional hypoperfusion could be
assessed with ultrahigh-frequency myocardial contrast echocardiography (MCE) and a
novel strategy of depot contrast enhancement. MCE was performed with 30-MHz
transthoracic imaging 10 seconds and 10 minutes after intravenous administration of
microbubbles in control mice, and in mice after left anterior descending coronary artery …