Minimal residual disease in leukaemia patients
T Szczepariski, A Orfão, VHJ van der Valden… - The lancet …, 2001 - thelancet.com
Because of developments in diagnosis of haemopoietic malignant diseases during the past
two decades, routine and reliable identification of very low numbers of malignant cells,
known as minimal residual disease (MRD), is now possible. Several large-scale studies
have shown that monitoring of MRD in haemopoietic malignant disease predicts clinical
outcome. In acute lymphoblastic leukaemia, MRD detection is useful for evaluating early
response to treatment and consequently for improving stratification, including treatment …
two decades, routine and reliable identification of very low numbers of malignant cells,
known as minimal residual disease (MRD), is now possible. Several large-scale studies
have shown that monitoring of MRD in haemopoietic malignant disease predicts clinical
outcome. In acute lymphoblastic leukaemia, MRD detection is useful for evaluating early
response to treatment and consequently for improving stratification, including treatment …
Determination of minimal residual disease in leukaemia patients.
D Campana - British journal of haematology, 2003 - search.ebscohost.com
Discusses relative advantages and disadvantages of minimal residual disease (MRD) assay
in patients with acute leukemia. Clinical and biological features of the disease; Techniques
for monitoring MRD; Observance of association between MRD and risk of relapse in children
and adult patients.
in patients with acute leukemia. Clinical and biological features of the disease; Techniques
for monitoring MRD; Observance of association between MRD and risk of relapse in children
and adult patients.
