Gut infections often lead to epithelial cell damage followed by a healing response. We
examined changes in the epithelial cell cytoskeleton and the involvement of host adaptive
immunity in these events using an in vivo model of parasitic infection. We found that both
ezrin and villin, key components of the actin cytoskeleton comprising the brush border (BB)
of intestinal epithelial cells (IECs), underwent significant post-translational changes
following gut infection and during the recovery phase of gut infection. Intriguingly, using mice …