Methods

I searched Medline from January 1991 until September 2001 using the terms “peripheral neuropathy” and “guideline.” The search yielded 11 references, including useful guidelines for the diagnosis and management of diabetic peripheral neuropathy, 2 but no guidelines on the diagnosis and management of generic peripheral neuropathy. This article offers a personal approach to the management of generalised peripheral neuropathy from the perspective of a neurologist with a special interest in the topic. The recommendations also take account of reviews published by authorities in peripheral neuropathy (see educational resources) and a recent audit of a Dutch departmental guideline that showed the value of investigating common causes before doing electrophysiological tests. 3