Viral infections remain a major cause of morbidity and mortality after pediatric hematopoietic
stem cell transplantation. Adoptive transfer of donor-derived virus-specific T cells can
reconstitute antiviral immunity in recipients and be effective both in preventing and treating
cytomegalovirus, Epstein–Barr virus and adenovirus infection. Current efforts are focused on
providing protection toward a broader range of viruses safely, rapidly and effectively.