Importance Risk factors for abdominal aortic aneurysm (AAA) are largely unknown, which
has hampered the development of nonsurgical treatments to alter the natural history of
disease. Objective To investigate the association between lipid-associated single-nucleotide
polymorphisms (SNPs) and AAA risk. Design, Setting, and Participants Genetic risk scores,
composed of lipid trait–associated SNPs, were constructed and tested for their association
with AAA using conventional (inverse-variance weighted) mendelian randomization (MR) …