[PDF][PDF] HIF-1α in colorectal carcinoma: Review of the literature

M Ioannou, E Paraskeva, K Baxevanidou, G Simos… - J buon, 2015 - jbuon.com
M Ioannou, E Paraskeva, K Baxevanidou, G Simos, R Papamichali, C Papacharalambous…
J buon, 2015jbuon.com
Herein, an overview of the HIF-1α expression in CRC is presented. This review delineates
the crucial role that HIF-1α plays in carcinogenesis, tumor angiogenesis and cancer
progression. The evaluation of HIF-1α in patient biopsies could be useful as a prognostic
and/or predictive biomarker in personalized cancer treatment.
Herein, an overview of the HIF-1α expression in CRC is presented. This review delineates the crucial role that HIF-1α plays in carcinogenesis, tumor angiogenesis and cancer progression. The evaluation of HIF-1α in patient biopsies could be useful as a prognostic and/or predictive biomarker in personalized cancer treatment.
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