[HTML][HTML] Identification and characterization of propionylation at histone H3 lysine 23 in mammalian cells
B Liu, Y Lin, A Darwanto, X Song, G Xu… - Journal of Biological …, 2009 - ASBMB
Propionylation has been identified recently as a new type of protein post-translational
modification. Bacterial propionyl-CoA synthetase and human histone H4 are propionylated
at specific lysine residues that have been known previously to be acetylated. However, other
proteins subject to this modification remain to be identified, and the modifying enzymes
involved need to be characterized. In this work, we report the discovery of histone H3
propionylation in mammalian cells. Propionylation at H3 lysine Lys 23 was detected in the …
modification. Bacterial propionyl-CoA synthetase and human histone H4 are propionylated
at specific lysine residues that have been known previously to be acetylated. However, other
proteins subject to this modification remain to be identified, and the modifying enzymes
involved need to be characterized. In this work, we report the discovery of histone H3
propionylation in mammalian cells. Propionylation at H3 lysine Lys 23 was detected in the …